Better known by its trade name Prozac®, this drug – one of the SELECTIVE SEROTONINREUPTAKE INHIBITORS (SSRIS) – has been widely used, especially in North America, for the treatment of depression and anxiety (see MENTAL ILLNESS). Though causing fewer side-eﬀects than TRICYCLIC ANTIDEPRESSANT DRUGS (the ﬁrst such drugs widely used), SSRI drugs should be prescribed with care and should not be stopped abruptly. Unlike benzodiazepine tranquillisers such as Valium®, ﬂuoxetine is not addictive, but there have been rare reports of it allegedly provoking people to acts of violence. The drug acts by modifying the activities of neurotransmitters, notably DOPAMINE and SEROTONIN in the brain, thus prolonging the eﬀects of these chemical messengers.
Article Categories:Medical Dictionary