Apr 6, 2014
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A substance formed in the BLOOD as it clots: indeed, its formation causes clotting. The substance is produced in threads; after the threads have formed a close meshwork through the blood, they contract, and produce a dense, felted mass. The substance is formed not only from shed blood but also from LYMPH which exudes from the lymph vessels. Thus fibrin is found in all inflammatory conditions within serous cavities like the PLEURA, PERITONEUM, and PERICARDIUM, and forms a thick coat upon the surface of the inflamed membranes. It is also found in inflamed joints, and in the lung as a result of pneumonia. (See COAGULATION.)

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Medical Dictionary

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