Apr 6, 2014
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Disulfiram is used as an adjunct in the treatment of alcoholism. It is relatively non-toxic by itself, but when taken in conjunction with alcohol it produces most unpleasant effects: for example, flushing of the face, palpitations, a sense of oppression and distress, and ultimately sickness and vomiting. The rationale of treatment therefore is to give the alcoholic subject a course of disulfiram and then demonstrate, by letting him or her take some alcoholic liquor, how unpleasant are the effects. If the patient is co-operative, the treatment may be effective, but there is some risk so it must be given under skilled medical supervision.

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Medical Dictionary

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