A muscle-relaxing drug, indicated for chronic severe spasticity (see SPASTIC) of voluntary muscle such as may occur after a STROKE or in CEREBRAL PALSY and MULTIPLE SCLEROSIS (MS). Unlike most other relaxants, it acts directly on the muscle, thus producing fewer centralnervous-system side-eﬀects. It is contraindicated if liver function is impaired, and is not recommended for children or for acute muscle spasm. It may cause drowsiness, resulting in impaired performance at skilled tasks and driving.
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