Feb 12, 2014
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Family ► Ranunculaceae.

Habitat ► Mishmi Hills in Arunachal Pradesh. Cultivated commercially in China.

Ayurvedic ► Mamira, Maamiraa, Tiktamuulaa. (Pita-muulikaa and Hem-tantu are provisional synonyms.)

Unani ► Maamisaa, Maamiraa.

Folk ► Titaa (Bengal and Assam).

Action ► Stomachic, antiperiodic, antibacterial, antifungal. Prescribed in debility, convalescence, intermittent fevers, dyspepsia, dysentery and intestinal catarrh. Used as a local application in thrush.

The rhizomes contains berberine (9%) as the major alkaloid; other alkaloids present are: coptin (0.08%), cop- tisin 0.02%) and jatrorrhizine (0.01%). Samples from China contained 9.2612.23% berberine, 2.39-3.25% coptisin and 3.20-4.46% jatrorrhizine. In China, the herb is used as an antidiabetic; the ethanolic (50%) extract exhibited hypoglycaemic and hypotensive activity.

The drug due to berberine and its related alkaloids promoted reticuloen- dothelium to increased phagocytosis of leucocytes in dog blood in vitro and in vivo.

Coptis chinensis (Huang Lian) inhibited erythrocyte haemolysis, decreased lipid peroxidation in brain and kidney, decreased generation of superoxide peroxidation and decreased hy- droxyl radicals in rats. (Life Sci, 2000, 66(8), 725-735.)

Dosage ► Root—1-3 g powder. (CCRAS.)

Article Categories:
Indian Medicinal Plants

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