Feb 12, 2014
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CHONEMORPHA MACROPHYLLA

Written by

(Roxb.) G. Don.

Synonym ► C. fragrans (Moon) Alston.

Family ► Apocynaceae.

Habitat ► Dense moist forests throughout India up to 1,500 m altitude.

English ► Wood Vine.

Ayurvedic ► Used in the Southern states as Muurvaa.

Action ► Powdered root and stems— laxative, antibilious.

A lignan derivative has been isolated from the stem. It accelerated uptake of low density lipoprotein by Hep G2 cell by 67.0%.

The root bark contains 3.03% of total alkaloids consisting mainly of chonemorphine. Chonemorphine di- hydrochloride is an anti-amoebic principle. It showed in vitro activity against Entamoeba histolytica and trichomo- nas vaginalis. It proved efficacious against hepatic amoebiasis in golden hamsters and intestinal amoebiasis in Wister rats.

Article Categories:
Indian Medicinal Plants

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