Candidosis (moniliasis) is an infection with the yeast, Candida albicans. It is encouraged by pregnancy, DIABETES MELLITUS, prolonged wide-spectrum ANTIBIOTICS or CORTICOSTEROIDS therapy, and is also seen in debilitated infants, the elderly and immunocompromised patients, e.g. those with AIDS/HIV. It may cause white patches in the mouth or vulvovaginal area (thrush) and a red vesicular and scaly rash in the ﬁnger clefts, beneath the breasts or in the groin or anogenital folds. Fingernail-fold infection causes chronic PARONYCHIA with secondary nail DYSTROPHY and may complicate RAYNAUD’S DISEASE. CLOTRIMAZOLE and similar ‘azoles’ as creams, oral gels or vaginal pessaries are rapidly eﬀective, but severe systemic infections require oral itraconazole or even intravenous AMPHOTERICIN B.
Article Categories:Medical Dictionary