A local anaesthetic, about four times as potent as LIDOCAINE. It has a slow onset of action (up to 30 minutes for full eﬀect), but its eﬀect lasts up to eight hours, making it particularly suitable for continuous epidural analgesia in labour (see PREGNANCY AND LABOUR). It is commonly used for spinal anaesthesia, particularly lumbar epidural blockade (see ANAESTHESIA). It is contraindicated in intravenous regional anaesthesia.
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