Bisphosphonates, of which disodium etidronate is one, are a group of drugs used mainly in the treatment of PAGET’S DISEASE OF BONE and in established vertebral osteoporosis (see BONE, DISORDERS OF). Their advantage over CALCITONIN (which has to be given by subcutaneous or intramuscular injection) is that they can be taken orally. They act by reducing the increased rate of bone turnover associated with the disease. Disodium etidronate is used with calcium carbonate in a 90-day cycle (duration of therapy up to three years) in the treatment of osteoporosis.
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