Acetazolamide is a sulphonamide drug which acts by inhibiting the ENZYME, carbonic anhydrase. This enzyme is of great importance in the production of acid and alkaline secretions in the body. Acetazolamide is sometimes used as a second-line drug for partial seizures in EPILEPSY. It also has a diuretic action (see DIURETICS) and is used to treat GLAUCOMA. The drug has a range of side-eﬀects. Related agents include dorzolamide and brinzolamide, used as eye-drops in patients resistant to beta blockers or who have contraindications to them.
Article Categories:Medical Dictionary